ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2014, Vol. 23 ›› Issue (3): 289-293.

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系统性红斑狼疮、反复发热、全身多发脓肿

  

  • 出版日期:2014-06-28 发布日期:2014-07-02

Systemic multiple abscess and recurrent fever in a patient with systemic lupus erythematosus

  • Online:2014-06-28 Published:2014-07-02

摘要:

摘要 中年女性,临床表现为多系统损害,伴自身抗体阳性、补体低下,临床诊断为系统性红斑狼疮,肾活检病理改变为狼疮性肾炎Ⅳ型,给予甲泼尼龙总计2.5g冲击,后续口服泼尼松、他克莫司、霉酚酸酯治疗。随访中出现全身多发脓肿,伴反复发热,多处脓液培养均为豚鼠奴卡菌。该患者最终诊断为播散性奴卡菌病。

关键词: 系统性红斑狼疮, 多发脓肿, 播散性奴卡菌病, 豚鼠奴卡菌

Abstract:

ABSTRACT A 43-year-old female was characterized by multi-system damage, positive autoantibodies and hypocomplementemia. The renal histologic examiantion showed type IV lupus nephritis. Then regimen of intravenous methylprednisolone totaled 2.5g was prescribed, following with oral prednisone, tacrolimus and mycophenolate mofetil. During the follow-up, she was suffered with systemic multiple abscess and recurrent fever. Pus culture showed Nocardia otitidiscaviarum. The final diagnosis was disseminated nocardiosis.

Key words: systemic lupus erythematosus, multiple abscess, disseminated , nocardiosis, Nocardia otitidiscaviarum