关键词: 原发性肾病综合征 , 高凝状态 , 血栓栓塞 , 儿童

Abstract:

ABSTRACT  Patients with the nephrotic syndrome are at increased risk of developing hypercoagulable states and thromboembolism, the most common of which is renal vein thrombosis. There are several unanswered or controversial issues relating to the mechanisms of the hypercoagulability and thromboembolism in the nephrotic syndrome which include endothelial dysfunction, platelet activation, functional disequilibrium between coagulation and anticoagulation, and proteinuria, hypoproteinemia, hypercholesterolemia caused by NS. In the recent years, the mechanisms have been updated by many case-control studies.

Key words: primary nephrotic syndrome , hypercoagulability , thromboembolism , children