关键词: 热射病  , 多器官功能障碍综合征 , 急性肾损伤 , 高容量血液滤过

Abstract:

ABSTRACT   Objective: To investigate the clinical manifestations and effects of continuous high volume hemofiltration on patients with heatstroke multi-organ dysfunction syndrome (MODS) and to explore the indication of continuous blood purify (CBP) in these kind of patients. Methodology: Seven cases were diagnosed heatstroke as perspiration abundantly and coma during long-distance running or work in the weather of high temperature and humidity, they were accepted in emergency department of our hospital, the symptoms had not relieved after receiving cooling and sedative treatment, and MODS developed. Then they were changed to our department and received continuous high volume veno-venous hemofiltration (CVVHVHF). Their clinical manifestations and effects of CVVHVHF were observed. Results: In clinical, they had coma, tachycardia, tachypnea, AKI, electrolyte disturbance, lactic acidosis, hepatic lesion and clotting time prolonged. 2 cases with rhabdomyolysis, higher myoglobin and troponin were received CVVHVHF promptly, Ultimately, they had normal renal function, normal liver function, normal blood coagulation function and the acute kidney injure molecule declined to normal. 2 cases recovered slowly because they were received CVVHVF lately. One turned to other hospital because of psychiatric symptom. 2 cases died because of giving up treatment or receiving CVVHVF lately. Conclusion: The patients with Heatstroke and MODS can fully recover after taking a quick and correct treatment, the case who received CVVHVF lately has badly prognosis, and the case who received CVVHVF promptly could rehabilitate quickly.

Key words:  heat stroke   , multiple organ dysfunction syndrome  , acute kidney injury    , high volume veno-venous hemofiltration