肾移植术后人细小病毒B19感染

doi:10.3969/j.issn.1006-298X.2018.06.020

肾脏病与透析肾移植杂志 ›› 2018, Vol. 27 ›› Issue (6): 589-593.DOI: 10.3969/j.issn.1006-298X.2018.06.020

肾移植术后人细小病毒B19感染

出版日期:2018-12-28 发布日期:2019-01-21

Human parvovirus B19 infection after renal transplantation

Online:2018-12-28 Published:2019-01-21

摘要/Abstract

摘要：

青年男性，因慢性肾脏病5D期行右侧同种异体肾移植术，术后2个月血红蛋白逐渐下降，反复输血、注射红细胞生成素及调整免疫抑制剂后，仍进行性贫血，骨髓示红系增生减低，血清核酸学检查示人细小病毒（HPV）B19 DNA高滴度复制。最终诊断为HPV B19感染（纯红细胞再生障碍性贫血），予丙种球蛋白治疗，患者血清HPV B19 DNA复制明显下降，血红蛋白升至正常。因此，肾移植术后患者出现不明原因的血红蛋白下降，应注意排除HPV B19的感染。

关键词: 人细小病毒B19, 纯红细胞再生障碍性贫血, 肾移植术后

Abstract:

A 32yearold male was characterized by persistent anemia after renal transplantation，and the bone marrow examination suggested erythroid development with an absence of late normoblasts.After nucleic acid detection，the final diagnosis was pure red cell aplasia after the human parvovirus B19 (HPV B19)infection.After human gammaglobulin therapy，peripheral blood cell analysis showed HPV B19 DNA replication decreased significantly，and recovery of hemoglobin，suggesting that anemia was corrected.Therefore，patients after renal transplantation with persistent anemia of unknown origin，we need to alert HPV B19 infection.

Key words: human parvovirus B19, pure red cell aplasia, renal transplantation

胡娜娜,许书添,董建华，等. 肾移植术后人细小病毒B19感染[J]. 肾脏病与透析肾移植杂志, 2018, 27(6): 589-593.

HU Nana，XU Shutian，DONG Jianhua，et al. Human parvovirus B19 infection after renal transplantation[J]. Chinese Journal of Nephrology, Dialysis & Transplantation, 2018, 27(6): 589-593.

[1]	倪雪峰，文吉秋. 移植肾急性抗体介导的排斥反应合并单克隆IgG沉积的增生性肾小球肾炎[J]. 肾脏病与透析肾移植杂志, 2019, 28(1): 95-99.
[2]	金英，李世军，许书添. 肾移植术后，反复发热、腹泻、腹膜后淋巴结肿大[J]. 肾脏病与透析肾移植杂志, 2017, 26(3): 292-297.
[3]	倪雪峰\|程东瑞. 肾移植术后糖尿病的诊治进展[J]. 肾脏病与透析肾移植杂志, 2015, 24(3): 284-288.

ISSN 1006-298X CN 32-1425/R

肾移植术后人细小病毒B19感染

Human parvovirus B19 infection after renal transplantation

PDF

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 3

编辑推荐

Metrics

本文评价