关键词: 糖皮质激素性骨质疏松症, 骨折风险, 评估, 预防和治疗, 指南

Abstract:

Longterm use of glucocorticoids (GCs) may leads to glucocorticoidinduced osteoporosis (GIOP), which is an important public health problem and lacking of assessment evidence for interventions and treatment. The GIOP guidelines developed by the American College of Rheumatology (ACR) have now been updated to the third edition. This revised guidelines use a variety of measurement to rating the evidence, assessing the risk of GIOP fractures in adults and in special populations (eg, children, organ transplant recipients, women of childbearing potential, and people receiving highdose GC treatment), and to analyze the benefits and harms of treatment, providing guidance in the treatment decisionmaking for clinicians and patients, recommending optimal treatment to get the maximum benefit.

Key words: glucocorticoid-induced osteoporosis, fracture risk, assessment, prevention and treatment, guideline