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肾脏病与透析肾移植杂志 ›› 2025, Vol. 34 ›› Issue (5): 480-485.DOI: 10.3969/j.issn.1006⁃298X.2025.05.016

• 危重肾脏病 • 上一篇    下一篇

重症患者血液净化中心静脉导管深静脉血栓形成

  

  • 出版日期:2025-10-28 发布日期:2025-10-30

Central venous catheter⁃related deep vein thrombosis for blood purification in critically ill patients

  • Online:2025-10-28 Published:2025-10-30

摘要: 中心静脉导管深静脉血栓形成(CRDVT)是重症血液净化治疗常见的严重并发症,其发病机制复杂,涉及疾病因素和导管因素的交互作用。CRDVT 可导致导管功能障碍,甚至引发肺栓塞等严重并发症,增加重症患者死亡风险。血管超声是 CRDVT 首选筛查工具,计算机断层扫描血管造影和数字减影血管造影适用于深部静脉血栓的确诊。CRDVT 防治策略强调综合干预,包括置管环节的超声引导穿刺和导管选择,治疗环节的动态监测、导管拔除时机,以及个体化抗凝、溶栓治疗和滤器置入等。

关键词: 血液净化, 深静脉血栓形成, 中心静脉导管

Abstract: Central venous catheter⁃related deep vein thrombosis (CRDVT) is a common and serious complication of critical care blood purification therapy. Its pathogenesis is complex, involving the interaction of disease⁃related and catheter⁃related factors. CRDVT can lead to catheter dysfunction and even severe complications such as pulmonary embolism, increasing the mortality risk in critically ill patients. Vascular ultrasound is the preferred screening tool for CRDVT, while CT venography (CTV) and digital subtraction angiography (DSA) are suitable for the definitive diagnosis of deep vein thrombosis. Prevention and treatment strategies for CRDVT emphasize a comprehensive and integrated approach. This includes ultrasound⁃guided puncture and appropriate catheter selection during insertion, dynamic monitoring and timely removal of the catheter during treatment, as well as individualized anticoagulant therapy, thrombolysis, and filter placement.

Key words: blood purification, deep vein thrombosis, central venous catheter