Abstract:

ABSTRACT   Object：To discuss the feasibility of tissue-engineered blood vascular（TEBV） as hemodialysis access. Methodology：The recent literatures about TEBV as arteriovenous access for hemodialysis were widely reviewed. Animal and clinical studies were summarized and evaluated. Results：Vascular graft with sufficient mechanical properties can be built by sheet-based tissue engineering and effectiveness of grafts by simplified sheet-based tissue engineering were testified in a series of animal and clinical studies as arteriovenous access. Recently，a kind of TEBV grafts cultured in a bioreactor that delivers cyclic radial strain were tested in a baboon model as competent arterial bypass and may provide a readily available option for hemodialysis. Conclusion：It is feasible to use TEBV grafts to build hemodialysis access and worth of further study.

Key words: tissue-engineered blood vascular  , hemodialysis vascular access