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肾脏病与透析肾移植杂志 ›› 2012, Vol. 21 ›› Issue (5): 496-500.

• 论文 • 上一篇    

肾病综合征伴高热、皮下广泛坏死

  

  • 出版日期:2012-10-24 发布日期:2012-10-24

Nephrotic syndrome with fever and widespread subcutaneous necrosis

  • Online:2012-10-24 Published:2012-10-24

摘要:

摘 要 青年男性,临床为肾病综合征、血清肌酐轻度升高,肾活检确诊IgA肾病,肾小管损伤严重,长期以大剂量糖皮质激素联合免疫抑制剂治疗。近期洗澡后出现大面积皮肤红肿热痛,伴高热;血清隐球菌抗原阳性,皮肤病理符合隐球菌表现,皮损脓液及皮肤坏死组织培养确诊新生隐球菌感染。

关键词: 隐球菌病, 原发性, 皮肤

Abstract:

ABSTRACT A 23-year-old man developed severe necrotizing cellμlitis on both anterior and posterior of his trunk after kneading. The patient had been treated with corticosteroids over twenty months for nephrotic syndrome. Skin biopsy of the wound area revealed cutaneous vascμlitis and chronic inflammation with yeast-like organisms. The Periodic Acid Schiff staining supported that the structures were consistent with Cryptococcosis. A Cryptococcosus neoformans infection was confirmed by cμlture.
Key words

Key words: cryptococcosis,primary, , cutaneous