ISSN 1006-298X      CN 32-1425/R

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肾脏病与透析肾移植杂志 ›› 2017, Vol. 26 ›› Issue (1): 76-80.DOI: 10.3969/cndt.j.issn.1006-298X.2017.01.017

• 论文 • 上一篇    下一篇

血脂净化治疗的临床应用

  

  • 出版日期:2017-02-28 发布日期:2017-02-21

Clinical application of lipoprotein apheresis

  • Online:2017-02-28 Published:2017-02-21

摘要:

血脂净化治疗(LA)即采用体外循环血液净化方式对血液中血脂成分进行清除的一类方法的总称。脂质代谢紊乱在心血管疾病中的重要作用已经证实,调脂治疗的重要性也受到更多关注。对于一些标准调脂治疗效果不佳、治疗抵抗或治疗不耐受的患者,LA作为一种替代性治疗方案,在临床的使用亦日渐广泛。本文对LA临床应用的最新进展进行综述。

关键词: 血脂净化, 家族性高胆固醇血症, 脂蛋白a, 高三酰甘油血症

Abstract:

Lipoprotein apheresis is a kind of blood purification methods,which remove lipoprotein in the blood by the way of extracorporeal blood circulation.The important role of lipid metabolism disorders in cardiovascular disease (CVD) has been confirmed,and the importance of lipid modulation therapy (LMT) has received more attention. LA as an alternative treatment for some patients with poor efficacy for traditional therapy,treatment resistance or treatment intolerance,which is widely used in clinical practiceThis article will review the latest progress of the clinical application of LA.

Key words: lipoprotein apheresis, familial hypercholesterolemia, lipoprotein a, hypertriglyceridemia