Abstract:

ABSTRACT Objective：To investigate the strategy of early diagnosis，therapy and prognosis of transplant renal artery stenosis (TRAS), and to further evaluate the clinical curative efficacy and safety of TRAS with comprehensive care. Methodology:：The clinical data of six cases with TRAS were analyzed retrospectively. The clinical characteristics and diagnosis of TRAS，therapeutic effects，complications，and outcomes were summaried. Results：The clinical
features in patients with TRAS were resistant hypertension，kidney dysfunction，oliguria and transplant renal vascular murmur. The early diagnosis of TRAS mainly depends on color Doppler flow imaging (CDFI) and Dual-Source CT angiography (DSCTA). The treatment success rate was 100%, no severe complications were found in all the cases, and comprehensive therapy was satisfactory. During the follow-up period, all of patients with normal renal function, stable blood pressure, and living quality was good. Conclusion：Early diagnosis and appropriately comprehensive therapy play important role in reversing resistant hypertension and transplant renal damage caused by TRAS, which may contribute significantly to patients and allograft survival.

Key words: transplant renal artery stenosis, color Doppler flow imaging, Dual-source CT angiography, comprehensive therapy