Abstract: The International Society for Peritoneal Dialysis (ISPD) last published guidelines on prescribing peritoneal dialysis (PD) in 2006,which stated with the terminology “adequate dialysis” and focused primarily on targets for small solute removal volume control.By 2020,ISPD updated guide lines to propose highquality goaldirected PD.The present recommendations are updated on the following sections.Emphase the importance of quality of life in patients and PD is aimed to provide the best health outcome possible for an individual.PD should be prescribed using shared decisionmaking between the person doing PD and the care team.The PD prescription should take into account the local country resources.Management should focus on preserving kidney function.Paients fluid status,nutrition status and removal of toxins should be measured to help ensure the delivery of PD.PD should be modified prescription to minimize the burden of treatment on frail individuals.The discussion herein will introduce update of the guideline with practical experience of National Clinical Research Center of Kidney Diseases,and review current available literature on the research status.

Key words: peritoneal dialysate, adequate dialysis, high-quality goaldirected