Abstract:

As a major part of the chronic kidney diseasemineral and bone disorder (CKDMBD)，secondary hyperparathyroidism (SHPT) leads to skeletal and cardiovascular diseases, which affects the long term survival and life quality of patients. Current treatments for SHPT include dietary phosphorus restriction, modification of dialysis prescription, phosphate binders, calcitriol or vitamin D analogues, and calcimimetics. Parathyroidectomy (PTX) should be taken into account when pharmacologic therapy has failed either because of drug resistance or side effects. However, patients with serious cardiac and/or pulmonary comorbidities are at increased risk of complications of general anesthesia. In addition, reoperation in the neck region may be difficult. To alleviate clinical symptoms, thermal ablation can be introduced as a treatment alternative. This paper summarizes the operation procedure and precautions of this treatment modality for patients with severe SHPT as well as its clinical application and recent development.