Abstract: Medical research has entered the era of parallel fusion of big data and precision,the reliance on mathematical models,information materials and other theories and technologies has been greatly improved.The crossfusion of singlecell maps and genomic medicine has given birth to a new era of life science research.Artificial intelligence,as a typical crossdiscipline,is enabling us to understand and deal with the complex information of life at a more comprehensive,deeper and clearer level with its strong computing power.In the field of kidney disease,machine learning has been applied in disease prediction,patient clustering,aided diagnosis and treatment,genome medicine and other fields.Using artificial intelligence to solve clinical problems and constructing an accurate medical research model based on acquisition and integrated utilization of complex data will drive the innovation and development of clinical medicine.