Abstract: Ｏｂｊｅｃｔｉｖｅ：To investigate the effect of mild hypothermia on renal function recovery in renal transplant recipients.
Ｍｅｔｈｏｄｏｌｏｇｙ：The cases of organ donation after death completed in our hospital from July 2017 to January 2019 were retrospectively analyzed (age from 18～65 years),and the renal function recovery of transplant recipients was analyzed. The recipients were divided into hypothermia group and nonhypothermia group according to whether the donor was treated with mild hypothermia or not. The shortterm and mediumterm recovery of renal function after transplantation in the two groups were compared,including the incidence of delayed renal function (DGF) and primary nonfunctional function (PNF).
Ｒｅｓｕｌｔｓ：There were 26 donors and 49 recipients in the mild hypothermia group,24 donors and 45 recipients in the nonmild hypothermia group.There was no statistical significance in the comparison of donor age,perioperative urine volume and ICU stay in the two groups (P>005).There was no significant difference in receptor age and preoperative creatinine between the two groups (P>005).The incidence of DGF in the two groups was 408% and 1778%,respectively,which was statistically significant (P=003).No PNF was found in both groups.Serum creatinine values in the mild hypothermia group at one week and one month after surgery were lower than those in the nonmild hypothermia group,and were basically the same at 3 months and 6 months after surgery,but the differences were not statistically significant (P>005).
Ｃｏｎｃｌｕｓｉｏｎ：
Mild hypothermia can reduce the incidence of DGF,which is beneficial to the early recovery of renal transplant recipients,and has little effect on the renal function in the short and medium term.