Abstract: Post-transplant diabetes mellitus (PTDM) is one of the common metabolic complications after organ transplantation, which seriously affects the short-term and long-term survival of recipients. The use of hormones and immunosuppressants after an organ transplant may lead to insulin resistance, which can lead to the development of post-transplant diabetes. Magnesium is an important cation in the human body and is involved in important physiological functions in the body. Hypomagnesemia increases the risk of developing diabetes after transplantation; The main mechanism may be related to the involvement of magnesium in glucose transport and uptake, as well as the regulation of insulin sensitivity and secretion. This article will discuss the occurrence, risk factors, and mechanisms of hypomagnesemia and post-transplant diabetes after kidney transplantation.

Key words: renal transplantation, hypomagnesemia, post-transplant diabetes millitus, insulin resistance