Abstract:

ABSTRACT  Objective: To investigate the prevalence of nutritional risk and malnutrition in critically ill patients with kidney disease and prospectively observe the clinical efficacy of short-term nutritional support.  Methodology: Adult patients in renal ICU were enrolled from August, 2011 to June, 2012. Nutritional Risk Screening 2002 (NRS2002) was performed in all patients. The patients with a total score of ≥3 were decided to receive nutritional support therapy. Their nutritional parameters including BMI, the changes of body weight, and the serum concentrations of Alb, PA, TF and LC were examined. Results: Four hundred sixty six patients underwent NRS2002, Overall prevalence of nutritional risk was 25.1% and malnutrition was 87.3%. 137 patients, who were 76 males and 61 females with a mean age of 40.0±17.3 years old, received nutritional support therapy. Among them, food fortification in 23 cases (16.8%), enteral nutrition in 97cases (70.8%), parenteral nutrition in 2 cases (1.5%), enteral nutrition plus parenteral nutrition in 15 cases (10.9%).The energy intake were (15.4±7.3) Kcal/kg in first day, (20.9±8.2) Kcal/Kg in third day, and (22.3±8.5) Kcal/Kg in seventh day (P=0.001). The protein intake were 0.5±0.2g, 0.6±0.3g, and 0.7±0.3g respectively (P=0.001). After a week of nutritional support therapy, the serum concentrations of Alb, PA, TF and LC were increased significantly (p=0.001). The I/E of male and female were also increased respectively (P=0.044 and 0.248).  Conclusion: The prevalence of nutritional risk and malnutrition was 87.3%, 25.1% respectively in critically ill patients with kidney disease. After short-term nutritional support therapy, the serum concentrations of Alb, PA,TF and LC as well as abnormal distribution of body water were improved.

Key words: Key words , Critical renal disease Nutritional risk Multi-frequency bioelectrical impedance