促红细胞生成素产生细胞与肾脏纤维化

ISSN 1006-298X CN 32-1425/R

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中文

The cells which produced erythropoietin (EPO) in kidney is called renal EPOproducing cells (REPs). Insufficient production of EPO can cause renal anemia and anemia associated with chronic disease disorders. REPs transformed into scarforming myofibroblasts, resulting in renal fibrosis, chronic kidney disease (CKD) patients the EPOproducing ability of myofibroblasttransformed REPs (MFREPs) is decreased. Recently studies on REPs made great progress and the research is expected to become the treatment of renal anemia and renal interstitial fibrosis new target.

SHAO Fang,XIE Honglang

Chinese Journal of Nephrology, Dialysis & Transplantation . 2017, (5): 471 -475 . DOI: 10.3969/j.issn.1006-298X.2017.05.017