ISSN 1006-298X      CN 32-1425/R

Chinese Journal of Nephrology, Dialysis & Transplantation ›› 2016, Vol. 25 ›› Issue (4): 324-329.DOI: 10.3969/cndt.j.issn.1006-298X.2016.04.005

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Outcomes  of renal transplantation in patients with lupus nephritis

  

  • Online:2016-08-28 Published:2016-08-31

Abstract:

Objective:To investigate the outcome and clinical features of renal transplantation (RT) for recipients with lupus nephritis (LN).
Methodology:From March 1994 to December 2014, eighteen LN patients received RT were enrolled into this retrospective study. 72 nonLN patients with RT were regarded as control. Their clinical features, recurrence and prognosis were analyzed and compared.
Results:They were 5 males and 13 females with an average age of (33±7) years old in LN patients with RT. The median followup time was 528 in lupus group and 585 months in control group respectively. Nobody was died in lupus group and only one was died in control group. The graft survival rates for lupus patients were 100%, 889% and 833% at 1, 5 and 10 years respectively, similar to the control survival rates of 100%, 931% and 889% (P=058). Recurrent LN was detected in one patient, but  did not lead to graft failure.
Conclusion:Longterm graft survivals were similar in LN and nonLN RT recipients. Renal transplant is an alternative therapy for ESRD in this population.