Abstract:

Klotho is an antiaging gene. Previous studies showed that Klotho not only exerted antiaging function but also protected kidney. Recent researches have been reported that the function of klotho liked as a hormone. Klotho protein can act on remote targets, such as cardiovascular system. Since Klotho is highly expressed in kidney and can act on remote targets, the effect of Klotho on cardiovascular diseases in chronic kidney disease patients has been a hot spot in recent years. This article summaries the effect of Klotho on cardiovasular diseases in chronic kidney disease.