Abstract:

ABSTRACT Objective：To explore the distribution of cardiovascular calcification in maintenance hemodialysis (MHD) patients and its related factors. Methodology：One hundred fourty four patients with MHD were enrolled into this respective study. Coronary artery calcification score (CACS, Agaston score) was detected by spiral CT, abdominal aortic calcification score (AACS, Kauppila score) was determined by abdominal lateral radiographs, and the valve calcification was examined by cardiac ultrasound as well as the cardiovascular calcification index（CCI）was calculated . Results：The total calcification occurrence was 70.8%. The proportion of CACS beyond 100 was 50.7%. The proportion of AACS beyond 5 was 48.5%. In patients with valvular calcification, the mitral valve calcification (34.2%) was dominated. The calcification of the three parts developed with age and the duration of dialisys. Comparation of the two groups of patients with or without calcification of three parts showed differences between the age, duration of dialysis, body mass index, waist, ankle brachial index, serum creatinine, serum albumin, total cholesterol, low density lipoprotein, super sensitivity C reactive protein and whether diabetes patients. The age, long duration, hypercalcemia, anemia, dyslipidemia were independent risk factors for cardiovascular calcification. Cardiovascular calcification index have an excellent sensitivity and specificity comparing with CACS. Conclusion：The total calcification occurrence was 70.83%. The advanced age, long duration of dialysis, anemia, hypercalcemia, dyslipidemia were independent risk factors for cardiovascular calcification. CCI might be a better standard for cardiovascular calcification.

Key words: maintenance hemodialysis , coronary artery calcification, Abdominal aortic calcification, valvular calcification, cardiovascular calcification index