Abstract:

 Glomerular filtration rate (GFR) is an important index for evaluating kidney function, and also the important basis to classify for the chronic kidney disease (CKD). The equations for evaluating GFR are simple and can be widely used, which are CG（Cockcroft-Gault） equation , MDRD（Modification of Diet in Renal Disease）equation, CKD-EPI,modified MDRD equation, ruijin equation and cystatin equation. The aim of this review is to look for which equation is better to evaluate GFR. Through comparing their bias, precision, accuracy and other indices, which one is much better can determined. As a result, CG equation is better used in healthy people, but it is worse used in those who have kidney disease and it is affected by weight evidently. MDRD equation is better used in those of kidney disease, but it is worse used when GFR is high. CKD-EPI overcomes this disadvantage. Modified MDRD equation and ruijin equation are better used in Chinese people. Cystatin equation is better used in the early stage of kidney disease. No equation is perfect. So these equations need to be improved deeply or need to develop better equations to evaluate GFR.