Organ crosstalk in acute kidney injury with extracorporeal organ support therapy
Multiple organ dysfunction syndrome often have a signifcant impact on several distal organs,regardless of site of initial insult.Bidirectional interactions between distant organs are commonly referred to as organ crosstalk.Regardless of whether kidneys are initiating cause or secondarily involved in distal organ dysfunction,AKI has been shown to be independently risk factor of mortality.All forms of therapies where blood is extracted from the body and processed with specific devices and techniques can be defined as extracorporeal organ support (ECOS).Renal replacement therapy and extracorporeal membrane oxygenation have been routinely used in various ICU settings.Native to artifcial organ interaction in and artifcial to artifcial organ crosstalk affect prognosis in critical illness patients.
DONG Jianhua, GE Yongchun. Organ crosstalk in acute kidney injury with extracorporeal organ support therapy[J]. Chinese Journal of Nephrology, Dialysis & Transplantation, 2021, 30(1): 81-86.
