Abstract:

【Abstract】Mannan-binding lectin (MBL) deficiency has been classified as a commonly occurring immune disorder, affecting approximately 30% of the human population. MBL, being part of the innate immune system, supports the recognition of infectious pathogens，and activates the lectin pathway of the complement system. MBL2 gene polymorphisms are associated with quantitative and qualitative MBL abnormalities in the serum. This review focuses on the MBL and the role of it in kidney disease.

Key words: 【Key words】mannan-binding lectin (MBL)；small pattern recognition molecule (sPRM）；the lectin pathway of complement, the innate immune , kidney disease