Abstract:

Objective： To investigate the treatment of anemia in dialysis patients and the related factors.   Methodology： A total of 1632 dialysis patients of 12 hospital in Shanghai during 2008.8-2008.10 were enrolled.  Results: In 1396 patients whose Hb<110g/L,  97.42% patients had been treated with EPO,  95.48% and 94.78% in HD and PD patients respectively(p<0.05). There were 62.38% patients reached the Hb target（>110g/L）,with 70.53% in HD and 40.86% in PD patients(p<0.001). The mean Hb was 115.62±25.98 g/L in the patients who reached the Hb target, with116.73±24.66 g/L in HD and 111.95±20.69 g/L in PD patients(p<0.05) .In HD and PD patients, the mean dose of EPO was (142.83±45.82) U/(kg•w) and (155.30±33.78) U/(kg•w) (p<0.05). 40.44% patients were treated with iron, with 44.10% in HD and 21.27% in PD patients, 33.43% and 18.66% patients were treated with oral iron in HD and PD patients(p<0.001), 11.24% and 2.61% patients were treated with intravenous iron in HD and PD patients(p<0.001), the mean dose of intravenous iron was (98.94±12.11) mg/w and (215.47±33.12)mg/w in HD and PD patients(p<0.001). The mean dose of EPO and iron treatment rate in the patients who reached the Hb goal was significantly higer than in the patients who didn’t reached the Hb goal.  Conclusions: Most of the anemic patients on dialysis had been treated with EPO, but there were also a great quantity of patients hadn’t been treated with iron, especially with intravenous iron which results a low rate of recheached Hb target. It is important to pay more attention in the treatment of anemia in dialysis patients.

Key words: anemia, dialysis, , erythropoeitin, , iron