Abstract:

OBJECTIVE：To analyse the clinical experience in patients with living donor kidney transplantation in XinJiang area. METHODOLOGY： One hundred and seventy-six patients with living donor kidney transplantion in XinJiang area from August 1999 to September 2008 were enrolled in this retrospective study. Their general conditions, the incidence of acute rejection and the way of immunosuppressive agents were investigated. RESULT: They were 144 male and 32 female with a mean of 37.0±10.3 years old. The minority nationality were 132 patients. The living donor kidney transplantation was occupied only 5% in the same period in all kidney transplantation before 2006, but after 2006, it was rising to 69.4% in all renal transplantation. The 1, 3, 5 , >5 year patient and graft survivals were 94.3% 93.2%, 92.0%, 88.6%, and 92.0%, 88.1%, 92.0% and 86.9%, repectively. The cumulative incidence of acute cellular rejection (ACR) were 9.1%. 18 patients sufferred from severe the lung infection, 11 patients died. CONCLUSION: The living donor transplantation was rapid growth in recent 3 years in XinJiang area, in which majority of patients was minorities ethnic (74.4%), while the donors were three generationgs of family members, at the same time the donor of Han ethnic were the family people. Our data showed that HLA-mismatch rate had no very close relationship with acute rejection.

Key words: Living donor, , Kidney transplantation, Minority