Abstract:

Ｏｂｊｅｃｔｉｖｅ：To investigate the prevalence and risk factors of hypercalcemia 6 and 12 months after kidney transplantation, and to reveal the natural history of serum calcium in recipients after kidney transplantation.
Ｍｅｔｈｏｄｏｌｏｇｙ：From November 2013 to March 2015, a total of one hundred fifteen patients with kidney transplant were prospectively and consecutively recruited from National Clinical Research Center of Kidney Diseases, Jinling Hospital and enrolled in this study. The followup period was 12 months. The prevalence and risk factors of hypercalcemia 6 and 12 months after kidney transplantation were analyzed.
Ｒｅｓｕｌｔｓ：Serum calcium levels were increased, and the prevalence of hypercalcemia (corrected serum calcium >25 mmol/L) was 426%, 339%, and 391% in our kidney transplant recipients at 3, 6, 12 months respectively. Serum calcium levels were lower than 30 mmol/L in all the 115 patients after kidney transplantation. Multivariate linear regression analysis revealed that preoperative intact parathyroid hormone (iPTH) was the best correlating factor with hypercalcemia 6 and 12 months after kidney transplantation.
Ｃｏｎｃｌｕｓｉｏｎ：Hypercalcemia could happen in 30%~40% patients within 12 months after kidney transplantation. The preoperative treatment of hyperparathyroidism may help to offer better management of hypercalcemia after kidney transplantation.